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The binding of heparin to cTnI may possibly decrease immunoreactivity, depending on the heparin focus in sample collection tubes (e.g., heparin in a focus of ninety U/mL is claimed to lead to a lower of approximately twenty% in cTnI concentration).[33] The influence of heparin on cTnI immunoassays could possibly be induced by variations throughout the sample matrix.
The laboratory should take part in the external quality Handle or proficiency screening (PT) system as it is a regulatory necessity released with the Facilities for Medicare and Medicaid Solutions (CMS) within the Medical Laboratory Improvement Amendments (CLIA) rules.[103] It is helpful to make sure the accuracy and dependability with the laboratory regarding other laboratories carrying out the same or similar assays.
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